SIM2 POLYPEPTIDES AND POLYNUCLEOTIDES AND USES OF EACH IN DIAGNOSIS AND TREATMENT OF OVARIAN, BREAST AND LUNG CANCERS

摘要

ABSTRACTA method of diagnosing predisposition to, or presence of ovarian cancer, breast cancer and/or lung cancer in a subject is provided. The method comprises determining a level of SIM2 in a lung tissue, breast tissue and/or ovarian tissue of the subject, the level being correlatable with predisposition to, or presence or absence of the ovarian cancer, breast cancer and/or lung cancer, thereby diagnosing predisposition to, or presence of ovarian cancer, breast cancer and/or lung cancer in the subject.