| 发明名称 |
Treating hypertriglyceridemia with RXR agonists in combination with a PPARgamma agonist |
| 摘要 |
This invention relates to methods and compositions for the treatment of cardiovascular disease, hypertriglyceridemia, low levels of lipoprotein lipase, low levels of HDL cholesterol and for increasing adipocyte differentiation using an RXR agonist in combination with a PPAR gamma agonist such as a thiazolidinedione compound. <IMAGE>
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| 申请公布号 |
EP1426048(A2) |
申请公布日期 |
2004.06.09 |
| 申请号 |
EP20040002911 |
申请日期 |
1996.09.17 |
| 申请人 |
LIGAND PHARMACEUTICALS INCORPORATED |
发明人 |
HEYMAN, RICHARD A.;CESARIO, ROSEMARY;MUKHERJEE, RANJAN |
| 分类号 |
A61K45/00;A61K31/00;A61K31/19;A61K31/192;A61K31/20;A61K31/203;A61K31/235;A61K31/425;A61K31/426;A61K31/44;A61K31/4418;A61K31/4439;A61K31/455;A61K38/28;A61K45/06;A61P3/00;A61P3/06;A61P3/10;C07C57/50;C07C59/72;C07C63/49;C07C63/66;C07C65/28;C07C65/36;C07C251/48;C07D221/08;C07D265/34;C07D311/92;C07D317/30;G01N33/50;(IPC1-7):A61K31/192;A61K31/441;A61K31/443 |
主分类号 |
A61K45/00 |
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