| 发明名称 |
PYRIDAZINONE DERIVATIVES AS CDK2-INHIBITORS |
| 摘要 |
<p>The present invention relates to novel pyridazinone derivatives of the gener al formula (I), wherein A is A1 or A2; O A1= ~,N~R A2= NH R H O R is unsubstituted or at least monosubstituted C1-C10-alkyl, aryl, aryl (C1-C10- alkyl)-, heteroaryl, heteroaryl-(C1-C10-alkyl)-, heterocyclyl, heterocyclyl- (C1,-C10-alkyl)-, C3-C10-cycloalkyl, polycycloalkyl, C2-Cio alkenyl or C2-C1 0- alkinyl and Ar is unsubstituted or at least monosubstituted aryl or heteroar yl.</p> |
| 申请公布号 |
CA2518917(A1) |
申请公布日期 |
2004.06.03 |
| 申请号 |
CA20032518917 |
申请日期 |
2003.11.19 |
| 申请人 |
AVENTIS PHARMA S.A. |
发明人 |
MATTER, HANS;MUELLER, GUENTER;WILL, DAVID WILLIAM;ROONEY, THOMAS;STEINMETZ, ANKE;BAUDOIN, BERNARD;SCHOENAFINGER, KARL;NAUMANN, THORSTEN;LE SUISSE, DOMINIQUE;HOELDER, SWEN;HALLEY, FRANCK;TIRABOSCHI, GILLES;COMBEAU, CECILE;SASSOON, INGRID |
| 分类号 |
A61P3/00;A61P3/04;A61P3/10;A61P9/00;A61P9/12;A61P25/00;A61P25/02;A61P25/28;A61P35/00;A61P37/00;C07D237/14;C07D237/24;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D405/04;C07D405/14;C07D409/04;C07D409/14;C07D413/04;C07D417/14;C07D513/04;(IPC1-7):C07D401/04;C07D413/14;A61K31/501;A61K31/537 |
主分类号 |
A61P3/00 |
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