| 发明名称 |
Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one |
| 摘要 |
The present invention relates to a novel process for producing a delta-lactone of the formula:using an acyl halide of the formula:wherein R<1>, R<2 >R<3 >and X are described herein, as well as novel intermediates. In particular, the present invention relates to a process for enantioselectively producing the (R)-delta-lactone.
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| 申请公布号 |
US6743927(B2) |
申请公布日期 |
2004.06.01 |
| 申请号 |
US20030364547 |
申请日期 |
2003.02.10 |
| 申请人 |
ROCHE COLORADO CORPORATION |
发明人 |
FLEMING MICHAEL P.;HAN YEUN-KWEI;HODGES LEWIS M.;JOHNSTON DAVID A.;MICHELI ROGER P.;PUENTENER KURT;ROBERTS CHRIS R.;SCALONE MICHELANGELO;SCHWINDT MARK A.;TOPPING ROBERT J. |
| 分类号 |
C07B61/00;C07C67/30;C07C67/31;C07D305/12;C07D309/32;C07F3/02;(IPC1-7):C07D309/32 |
主分类号 |
C07B61/00 |
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