| 发明名称 |
TRI-SUBSTITUTED IMIDAZOLES HAVING MULTIPLE THERAPEUTIC PROPERTIES |
| 摘要 |
PROBLEM TO BE SOLVED: To inhibit cytokines and treatment of a cytokine mediated disease, in a mammal in need thereof and to provide a medical treatment of the same. SOLUTION: The medicinal composition comprises the compounds expressed by formula (II). The pharmaceutical composition comprises a compound of formula (II) and a pharmaceutically acceptable diluent or carrier. 4-Fluorophenyl-tolylthiomethyl isocyanide is an example of the compound expressed by formula (II). COPYRIGHT: (C)2004,JPO
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| 申请公布号 |
JP2004149541(A) |
申请公布日期 |
2004.05.27 |
| 申请号 |
JP20030412024 |
申请日期 |
2003.12.10 |
| 申请人 |
SMITHKLINE BEECHAM CORP |
发明人 |
ADAMS JERRY LEROY;SHELDRAKE PETER WILLIAM;GALLAGHER TIMOTHY FRANCIS;GARIGIPATI RAVI SHANKER;BENDER PAUL ELLIOT;BOEHM JEFFREY C |
| 分类号 |
A61K8/19;A61K8/00;A61K8/20;A61K8/23;A61K31/415;A61K31/4168;A61K31/4178;A61K31/44;A61K31/4409;A61K31/4427;A61K31/4439;A61K31/445;A61K31/4545;A61K31/47;A61K31/505;A61K31/506;A61K31/535;A61K31/5377;A61P1/00;A61P1/04;A61P3/00;A61P3/10;A61P9/10;A61P11/00;A61P11/06;A61P17/06;A61P19/00;A61P19/02;A61P19/08;A61P21/00;A61P25/28;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P37/00;A61P39/00;A61P43/00;A61Q1/00;A61Q1/12;A61Q19/00;C07B61/00;C07C231/12;C07C309/46;C07C315/02;C07C317/28;C07C317/40;C07C319/14;C07C319/20;C07C323/29;C07C323/32;C07C323/41;C07C323/45;C07D;C07D213/53;C07D213/61;C07D215/12;C07D239/38;C07D239/42;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D403/14;C07D405/14;C07D413/04;C07D413/14;(IPC1-7):C07C323/45;A61K7/00;A61K7/48 |
主分类号 |
A61K8/19 |
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