发明名称 |
MODIFIED DENDRITIC CELLS |
摘要 |
Infection of a dendritic cell with a lentivirus impairs the dendritic cell's ability to act as an antigen presenting cell that polarizes a naïve T cell to develop along the Th1 pathway. This impairment is restored by infecting dendritic cells with lentiviruses containing vectors encoding IL-7, IL-12, and siRNA targeting IL-10 RNA. |
申请公布号 |
WO2004044147(A2) |
申请公布日期 |
2004.05.27 |
申请号 |
WO2003US35482 |
申请日期 |
2003.11.07 |
申请人 |
CHANG, LUNG-JI;CHEN, XIAOCHUAN |
发明人 |
CHANG, LUNG-JI;CHEN, XIAOCHUAN |
分类号 |
C07K14/54;C12N5/0784;C12N15/113 |
主分类号 |
C07K14/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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