ORAL DELIVERY OF MODIFIED TRANSFERRIN FUSION PROTEINS
摘要
Pharmaceutical compositions containing modified fusion proteins of transferrin and therapeutic proteins or peptides with increased serum half-life or increased serum stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, but does exhibit binding to iron and/or the transferrin receptor. Such fusion proteins may be administered orally.
申请公布号
WO2004019872(A3)
申请公布日期
2004.05.21
申请号
WO2003US26778
申请日期
2003.08.28
申请人
BIOREXIS PHARMACEUTICAL CORPORATION;PRIOR, CHRISTOPHER, P.;SADEGHI, HOMAYOUN;TURNER, ANDREW
发明人
PRIOR, CHRISTOPHER, P.;SADEGHI, HOMAYOUN;TURNER, ANDREW