发明名称 |
METHOD AND PROBES FOR THE DETECTION OF A TUNOR SPECIFIC FUSION PROTEIN |
摘要 |
<p>This invention relates to the detection of fusion proteins. The invention provides a set of at least a first and a second molecular probe, each probe provided with a dye wherein said dyes together allow energy transfer; at least one probe provided with a reactive group allowing juxtaposing said at least first and second probe wherein said reactive group allows to modulate juxtaposing said probes such that there is an increased likelihood of energy transfer between said dyes. A method is provided which permits detecting the presence of a fusion protein in a cell at the single cell level.</p> |
申请公布号 |
WO2004042398(A1) |
申请公布日期 |
2004.05.21 |
申请号 |
WO2003NL00776 |
申请日期 |
2003.11.06 |
申请人 |
ERASMUS UNIVERSITEIT ROTTERDAM;VAN DONGEN, JACOBUS, JOHANNES, MARIA |
发明人 |
VAN DONGEN, JACOBUS, JOHANNES, MARIA |
分类号 |
G01N33/542;G01N33/574;(IPC1-7):G01N33/542 |
主分类号 |
G01N33/542 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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