发明名称 |
Stable radioiodine conjugates and methods for their systhesis |
摘要 |
Methods are described for conjugating radioiodinated peptides to non-metabolizable carbohydrates with improved yields and qualities of conjugates. Radioiodinated residualizing antibody conjugates comprising a carbohydrate-appended peptide are also provided. The instant radioiodinated residualizing antibody conjugates are particularly stable in vivo and are suitable for radioimmunodetection and radioimmunotherapy. |
申请公布号 |
US2004096394(A1) |
申请公布日期 |
2004.05.20 |
申请号 |
US20030713268 |
申请日期 |
2003.11.17 |
申请人 |
IMMUNOMEDICS, INC. |
发明人 |
GOVINDAN SERENGULAM V. |
分类号 |
A61K51/04;A61K51/08;A61K51/10;C07H3/04;C07K1/107;G01N33/543;(IPC1-7):C07K16/46;C07K14/47;A61K51/00 |
主分类号 |
A61K51/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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