METHODS FOR TREATMENT OF THIOL-CONTAINING COMPOUND DEFICIENT CONDITIONS
摘要
Methods for therapy of cystic fibrosis and other conditions are provided. The methods comprise one or more agents capable of increasing thiol-containing compound transport via a transporter system (i.e. ABC transporters such as MDR-1 or MRP-2) in cells. Other embodiments include the use of agents to modulate transport of thiol-containing compounds within the cell. Therapeutic methods involve the administration of such agents to a patient afflicted with cystic fibrosis and/or another condition responsive to stimulation of thiol-containing compound transport.
申请公布号
WO2004042020(A2)
申请公布日期
2004.05.21
申请号
WO2003US34723
申请日期
2003.10.30
申请人
NATIONAL JEWISH MEDICAL AND RESEARCH CENTER;DAY, BRIAN, J.;VELSOR, LEONARD, W.