| 发明名称 |
SUBSTITUTED N-PHENYL 2-HYDROXY-2-METHYL-3,3,3-TRIFLUROPROPANAMIDE DERIVATIVES WHICH ELEVATE PYRUVATE DEHYDROGENASE ACTIVITY. |
| 摘要 |
<p>Compounds of formula (I) wherein R is methyl or mesyl; and pharmaceutically acceptable salts and in vivo hydrolysable esters thereof are described. Also described are processes for their preparation, pharmaceutical compositions containing it and their use in producing an elevation of PDH activity in a warm-blooded animal.</p> |
| 申请公布号 |
MXPA04001552(A) |
申请公布日期 |
2004.05.17 |
| 申请号 |
MX2004PA01552 |
申请日期 |
2002.08.21 |
| 申请人 |
ASTRAZENECA AB |
发明人 |
ROGER JOHN BUTLIN |
| 分类号 |
C07D295/12;A61K31/495;A61P3/04;A61P43/00;C07D295/096;C07D295/26;(IPC1-7):A61K31/165;C07D295/22;A61K31/18 |
主分类号 |
C07D295/12 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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