USE OF PIPERAZINE SULFONIC ACID DERIVATIVES AS CCR1 ANTAGONISTS FOR THE TREATMENT OF FIBROSIS, ALZHEIMER DISEASE AND OTHER DISORDERS

摘要

The present invention relates to methods of using CCR1 antagonists as immunomodulatory agents. In particular, the methods relate to using compounds of the formula (I) or the pharmaceutically acceptable salt thereof; wherein X, Y, a, b, c, d, R<1>, R<2>, R<3> and R<5> are as defined herein.