发明名称 |
Humanised antibodies to the epidermal growth factor receptor |
摘要 |
The present invention provides a humanised form of the antibody 340 obtainable from the cell line deposited with the ECACC under accession number 97021428. Such antibodies have been found to have an increased ability to kill cells compared to the murine antibody 340. Also provided are nucleic acids encoding such antibodies, as well as the use of the antibodies in medicine, in particular in the treatment of cancer.
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申请公布号 |
US2004091485(A1) |
申请公布日期 |
2004.05.13 |
申请号 |
US20030258728 |
申请日期 |
2003.06.18 |
申请人 |
ELLIS JOHN ROBERT MAXWELL;DURRANT LINDA GILLIAN |
发明人 |
ELLIS JOHN ROBERT MAXWELL;DURRANT LINDA GILLIAN |
分类号 |
C12N15/09;A61K31/7088;A61K39/395;A61P35/00;C07K16/28;C07K16/46;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/13;C12P21/02;(IPC1-7):A61K39/395;C07H21/04;C07K16/30;C12N5/06 |
主分类号 |
C12N15/09 |
代理机构 |
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地址 |
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