PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE, TYPE II BETA INHIBITORS FOR INHIBITING ANGIOGENESIS

摘要

Compounds, compositions and methods are provided for modulating the expression of phosphatidylinositol-4­- phosphate 5-kinase, type II beta. The compositions comprise oligonucleotides, targeted to nucleic acid encoding phosphatidylinositol-4-phosphate 5-kinase, type II beta. Methods of using these compounds for modulation of phosphatidylinositol-4-phosphate 5-kinase, type II beta expression and for diagnosis and treatment of disease associated with expression of phosphatidylinositol-4­phosphate 5-kinase, type II beta are provided.