发明名称 Alkyl-[4-(difluorophenyl)-oxazol-5-yl]-triazolo-pyridines
摘要 The present invention relates to novel alkyl-[4-(difluorophenyl)-oxazol-5-yl]-triazolo-pyridines, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use. The compounds of the present invention are potent inhibitors of MAP kinases, preferably p38 kinase. They are useful in the treatment of inflammation, osteoarthritis, rheumatoid arthritis, cancer, reperfusion or ischemia in stroke or heart attack, autoimmune diseases and other disorders.
申请公布号 US2004092547(A1) 申请公布日期 2004.05.13
申请号 US20030649227 申请日期 2003.08.27
申请人 PFIZER INC 发明人 DOMBROSKI MARK A.;LETAVIC MICHAEL A.;MCCLURE KIM F.
分类号 C07D471/04;(IPC1-7):A61K31/474;C07D471/02 主分类号 C07D471/04
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