发明名称 |
CARDIAC MUSCLE REGENERATION USING MESENCHYMAL STEM CELLS |
摘要 |
<p>Disclosed is a method for producing cardiomyocytes in vivo by administering to the heart of an individual a cardiomyocyte producing amount of mesenchymal stem cells. These cells can be administered as a liquid injectible or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.</p> |
申请公布号 |
AU2003284320(A1) |
申请公布日期 |
2004.05.13 |
申请号 |
AU20030284320 |
申请日期 |
2003.10.22 |
申请人 |
OSIRIS THERAPEUTICS, INC. |
发明人 |
ALASTAIR, MORGAN MACKAY;BRADLEY, J. MARTIN;MARK, F. PITTENGER;STEPHEN, L. GORDON |
分类号 |
A61K35/12;A61K48/00;C12N5/02;C12N5/077;C12N5/0775 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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