发明名称 |
METHOD FOR EVALUATING DEGREE OF CANCERATION IN SAMPLE ORIGINATING FROM MAMMAL |
摘要 |
PROBLEM TO BE SOLVED: To provide a method for evaluating a degree of canceration in a sample originating from a mammal based on detection of gene abnormality useful for evaluating a diagnostic method, a therapeutic method and the like for finding out cancers in an early stage. SOLUTION: The method for evaluating the degree of canceration in the sample originating from the mammal comprises (1) a first process for measuring methylation frequency of HAND1 gene included in the sample originating from the mammal or an index-value relatively relating to the same and (2) a second process for judging the degree of canceration of the sample depending on difference given by comparing the methylation frequency or the index-value relatively relating to the same measured in the process (1) with a control. COPYRIGHT: (C)2004,JPO
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申请公布号 |
JP2004135661(A) |
申请公布日期 |
2004.05.13 |
申请号 |
JP20030325744 |
申请日期 |
2003.09.18 |
申请人 |
NATIONAL CANCER CENTER-JAPAN;SUMITOMO CHEM CO LTD |
发明人 |
USHIJIMA TOSHIKAZU;KANEDA ATSUSHI |
分类号 |
G01N33/50;A61K31/7068;A61K38/00;A61K45/00;A61K48/00;A61P35/00;C12N15/09;C12Q1/02;C12Q1/68;(IPC1-7):C12Q1/68;A61K31/706 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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