| 发明名称 |
ANTISENSE MODULATION OF APOLIPOPROTEIN(A) EXPRESSION |
| 摘要 |
<p>Antisense compounds, compositions and methods are provided for modulating the expression of apolipoprotein(a). The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding apolipoprotein(a). Methods of using these compounds for modulating of apolipoprotein(a) expression and for treatment of diseases associated with expression of apolipoprotein(a) are provided.</p> |
| 申请公布号 |
EP1417351(A2) |
申请公布日期 |
2004.05.12 |
| 申请号 |
EP20020794670 |
申请日期 |
2002.08.05 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
CROOKE, ROSANNE, M.;GRAHAM, MARK, J. |
| 分类号 |
C12N15/09;A61K31/7088;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P3/06;A61P9/00;A61P9/10;C12N15/113;(IPC1-7):C12Q1/68;C07H21/04;A61K31/07;A01N41/04 |
主分类号 |
C12N15/09 |
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