发明名称 |
Amino-substituted dihydropyrimido[4,5-D]pyrimidinone derivatives |
摘要 |
Compounds of formula I are described. These compounds are protein kinase inhibitors, in particular they inhibit the src family tyrosine kinases. Thus, these compounds are useful for the treatment of diseases mediated by src tyrosine kinases, including cell proliferative disorders such as cancer. Also described are methods of making and using compounds of formula I as well as pharmaceutical compositions containing these compounds.
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申请公布号 |
US2004087600(A1) |
申请公布日期 |
2004.05.06 |
申请号 |
US20030697543 |
申请日期 |
2003.10.30 |
申请人 |
CAI JIANPING;DIMOUDIS NIKOLAOS;HONOLD KONRAD;LUK KIN-CHUN;SCHEIBLICH STEFAN;SUDERGAT HILKE;TIEFENTHALER GEORG;TONN OLIVER |
发明人 |
CAI JIANPING;DIMOUDIS NIKOLAOS;HONOLD KONRAD;LUK KIN-CHUN;SCHEIBLICH STEFAN;SUDERGAT HILKE;TIEFENTHALER GEORG;TONN OLIVER |
分类号 |
A61K31/505;C07D317/72;C07D487/04;C07D491/10;(IPC1-7):C07D487/02;A61K31/519 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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