发明名称 |
PROTEIN ARRAYS AND USES THEREOF |
摘要 |
The inventors herein describe methods for the production of a functional human, animal, plant or microbe protein arrays and methods to assay for interactions between the proteins on the array with molecules of interest, for example, using such arrays to determine the in vitro metabolite profile of any drug. Such protein arrays can be used, for example, to assay, in a parallel fashion, the protein products of DNA sequences encoding drug metabolizing enzymes (DMES) to obtain a toxicology profile. Also described herein is a novel DME expression and purification strategy using detergents and not requiring an ultra-centrifugation step. |
申请公布号 |
AU2003280084(A1) |
申请公布日期 |
2004.04.30 |
申请号 |
AU20030280084 |
申请日期 |
2003.09.16 |
申请人 |
SENSE PROTEOMIC LIMITED |
发明人 |
DARREN, JAMES HART;NICHOLAS, A. BOCKETT;ROLAND KOZLOWSKI;JONATHAN, MARK BOUTELL;BENJAMIN, LESLIE, JAMES GODBER |
分类号 |
C07K1/04;C07K14/47;C12N9/02;C12Q1/26;C12Q1/68;C40B30/04;C40B40/06;C40B40/10;C40B60/14;G01N33/68 |
主分类号 |
C07K1/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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