发明名称 |
METHODS AND COMPOSITIONS FOR BLOOD POOL IDENTIFICATION, DRUG DISTRIBUTION QUANTIFICATION AND DRUG RELEASE VERIFICATION |
摘要 |
Methods and compositions useful for detecting an in vivo blood pool, monitoring the distribution of a compound of interest to a desired site in an organism by magnetic resonance imaging, monitoring the accumulation of a compound of interest at a desired site in vivo by magnetic resonance imaging, and monitoring the release of liposomal contents to an external stimulus at a desired site in vivo by magnetic resonance imaging are disclosed. Some compositions comprise envirosensitive or non-sensitive liposomes. Contrast agents, such as manganese-based compounds, are also disclosed. |
申请公布号 |
AU2003272341(A1) |
申请公布日期 |
2004.04.30 |
申请号 |
AU20030272341 |
申请日期 |
2003.09.11 |
申请人 |
DUKE UNIVERSITY |
发明人 |
BENJAMIN, L. VIGLIANTI;MARK, W. DEWHIRST;JAMES, R. MACFALL;ZELJKO VUJASKOVIC |
分类号 |
A61B;A61B5/05;A61B5/055;G01N24/00;G01N33/48;G01R33/48;G01V3/00 |
主分类号 |
A61B |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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