发明名称 TREATING ANDROGEN DECLINE IN AGING MALE (ADAM)-ASSOCIATED CONDITIONS WITH SARMS
摘要 The present invention provides a method of treating, preventing, suppressing , inhibiting or reducing the incidence of an Androgen Decline in Aging Male (ADAM)~- associated condition in a male subject, by administering to the subject a selective androgen receptor modulator (SARM) compound and/or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, prodrug, polymorph, crystal, or an y combination thereof. The present invention further provides a method of treating, preventing, suppressing, inhibiting or reducing the incidence of sexual dysfunction, decreased sexual libido, erectile dysfunction, hypogonadism, sarcopenia, osteopenia, osteoporosis, alterations in cognition and mood, depression, anemia, hair loss, obesity, benign prostate hyperplasi a or prostate cancer due to ADAM in a male subject, by administering to the subject a selective androgen receptor modulator (SARM) compound and/or its analog, derivative, isomer, metabolite, pharmaceutically acceptable salt, pharmaceutical product, hydrate, N-oxide, prodrug, polymorph, crystal, or an y combination thereof.
申请公布号 CA2501874(A1) 申请公布日期 2004.04.29
申请号 CA20032501874 申请日期 2003.10.14
申请人 GTX INC. 发明人 STEINER, MITCHELL S.;VEVERKA, KAREN A.;MILLER, DUANE D.;DALTON, JAMES T.
分类号 C07K14/72;(IPC1-7):A61K31/165;A61K31/40;A61K31/41;A61K31/435;A61K31/44 主分类号 C07K14/72
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