| 发明名称 |
CARDIOTOXIN MOLECULAR TOXICOLOGY MODELING |
| 摘要 |
The present invention is based on the elucidation of the global changes in gene expression and the identification of toxicity markers in tissues or cells exposed to a known cardiotoxin. The genes may be used as toxicity markers in drug screening and toxicity assays. The invention includes a database of genes characterized by toxin-induced differential expression that is designed for use with microarrays and other solid-phase probes. |
| 申请公布号 |
EP1412537(A2) |
申请公布日期 |
2004.04.28 |
| 申请号 |
EP20020806804 |
申请日期 |
2002.07.10 |
| 申请人 |
GENE LOGIC, INC. |
发明人 |
MENDRICK, DONNA;PORTER, MARK;JOHNSON, KORY;HIGGS, BRANDON;CASTLE, ARTHUR;ELASHOFF, MICHAEL |
| 分类号 |
C12N15/09;C12M1/00;C12Q1/02;C12Q1/68;G01N33/48;G01N33/50;G06F19/00;(IPC1-7):C12Q1/68;G06N3/12 |
主分类号 |
C12N15/09 |
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