USE OF SELECTIVE COX-2 INHIBITORS FOR PREPARATION OF PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF URINARY INCONTINENCE

摘要

The treatment of neuromuscular dysfunction of the lower urinary tract by compounds which selectively inhibit the COX-2 isozyme is described. The compounds concerned inhibit the COX-2 isozyme with a potency at least 10-fold, and preferably at least 100-fold, greater than their potency on the COX-1 isozyme.