摘要 |
The present invention relates to a method for cleaving chemical bonds whereby the activation energy for bond cleavage is delivered through space by a carrier molecule, which can be switched from its ground state to an excited state upon irradiation. Furthermore, the present invention relates to a device for the intermolecular transfer of bond cleavage activation energy from carrier molecules to target molecules of the bond to be cleaved comprising a storage tank, comprising said carrier molecules, means (113) for delivering said carrier molecules through an activation area (104), activation means (102) and an exchange area (101) comprising the target molecule. Furthermore, the present invention addresses the use of the method according to the invention for effecting the light-addressed 5' to 3' or 3' to 5' in-situ synthesis of nucleic acid derivatives on solid supports for the production of biochips or genechips. |