发明名称 DUAL BINDING SITE ACETYLCHOLINESTERASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
摘要 A family of compounds of formula (I) wherein: X is one of the following radicals: which behaves as dual site acetylcholinesterase inhibitors and which are especially useful for the treatment of cognitive disorders as senile dementia, cerebrovascular dementia, mild cognition impairment, attention deficit disorder, and/or neurodegenerative dementing disease with aberrant protein aggregations as specially Alzheimer's disease, Parkinson disease, ALS, or prion diseases, as Creutzfeldt-Jakob disease or Gerstmann-Straussler-Scheinher disease.
申请公布号 WO2004032929(A2) 申请公布日期 2004.04.22
申请号 WO2003GB04314 申请日期 2003.10.07
申请人 NEUROPHARMA SA;MARTINEZ GIL ANA;DORRONSORO DIAZ ISABEL;RUBIO ARRIETA LAURA;ALONSO GORDILLO DIANA;FUERTES HUERTA ANA;MORALES-ALCELAY SUSANA;DEL MONTE MILLAN MARIA;GARCIA PALOMERO ESTHER;USAN EGEA PAOLA;DE AUSTRIA CELIA;MEDINA PADILLA MIGUEL;RUFFLES GRAHAM KEITH 发明人 MARTINEZ GIL ANA;DORRONSORO DIAZ ISABEL;RUBIO ARRIETA LAURA;ALONSO GORDILLO DIANA;FUERTES HUERTA ANA;MORALES-ALCELAY SUSANA;DEL MONTE MILLAN MARIA;GARCIA PALOMERO ESTHER;USAN EGEA PAOLA;DE AUSTRIA CELIA;MEDINA PADILLA MIGUEL
分类号 A61K31/473;C07D219/12;C07D401/12;C07D417/12 主分类号 A61K31/473
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