| 摘要 |
<p>An oral preparation contains 0.01-5 wt.% of sulfosuccinic surfactant and 0.5-10 wt.% of a precipitated abrasive silica. The sulfosuccinic surfactant is of formula X 1C(O)CH 2C(CO 2X)SO 3M 1 (I). X 1, X 2one is R 1O(AO) n- or R 1C(O)B(AO) n- and the other is M 2O-; M 1, M 2H, alkali metal alkali earth metal, NH 4 or alkanol amine; R 18-22C alkyl or alkenyl group; AO : 2-3C oxyalkylene group; n : mean addition number of 0 -20; B : -NH- or 2-3C monoalkanol amine residue group The abrasive precipitated silica has a 50 percentile (d 5 0) particle diameter of 15 Microm or less, a 9 percentile (d 9 0) particle diameter of 15 Microm or less and an RDA value of 120 or more.</p> |
