发明名称 |
RECOMBINANT PLASMODIUM FALCIPARUM MEROZOITE PROTEIN-1/42 VACCINE |
摘要 |
This application is the expression and purification of a recombinant Plasmodium falciparum (3D7) MSP-142. The method of the present invention produces a highly purified protein which retains folding and disulfide bridging of the native molecule. The recombinant MSP-142 is useful as a diagnostic reagent, for use in antibody production, and as a vaccine. |
申请公布号 |
EP1409533(A2) |
申请公布日期 |
2004.04.21 |
申请号 |
EP20020717382 |
申请日期 |
2002.01.25 |
申请人 |
WALTER REED ARMY INSTITUTE OF RESEARCH |
发明人 |
LYON, JEFFREY, A.;ANGOV, EVELINA;COHEN, JOE, D.;VOSS, GERALD |
分类号 |
A61K39/00;A61K39/015;A61P33/06;C07K14/445;C12N1/21;C12N15/30 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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