CRYSTALLINE FORM OF MALIC ACID SALT OF N-|2-(DIETHYLAMINO)ETHYL|-5-|(5-FLUORO -2--OXO-3N-INDOL-3-YLIDENE)METHYL]-2,4- DIMELHYL-1N-PYRROLE-3-CARBOXAMIDE (VARIANTS), A METHOD FOR PREPARING AND COMPOSITIONS THEREOF

摘要

The present invention provides crystals, and compositions thereof, wherein the crystals include a malic acid salt of N-|2-(diethylamino)ethyl|-5-|(5-fluoro-l,2-dihydro-2-oxo-3||-indol-3-ylidene)melhyl|-2,4-dimelhyl-|||-pyrrole-3-carhoxamide. Methods of preparing such crystals are also disclosed.