| 发明名称 |
Derivatives of 3-(4-aminopyrrol-2-ylmethylidene-2-indolinone functioning as protein kinase inhibitors |
| 摘要 |
<p>The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.</p> |
| 申请公布号 |
CZ20032414(A3) |
申请公布日期 |
2004.04.14 |
| 申请号 |
CZ20030002414 |
申请日期 |
2002.02.15 |
| 申请人 |
SUGEN, INC;PHARMACIA & UPJOHN COMPANY |
发明人 |
GUAN HUIPING;LIANG CONGXIN;SUN LI;TANG PENG CHO;WEI CHUNG CHEN;MAURAGIS MICHAEL A.;VOJKOVSKY TOMAS;JIN OINGWU;HERRINGTON PAUL MATTHEW |
| 分类号 |
A61K31/404;A61K31/4178;A61K31/437;A61K31/5377;A61K31/541;A61P3/10;A61P9/00;A61P17/06;A61P19/02;A61P29/00;A61P35/00;C07D;C07D403/06;C07D403/14;C07D413/14;C07D471/04;(IPC1-7):C07D403/04;A61K31/537;A61K31/401;A61K31/41;C07D471/14 |
主分类号 |
A61K31/404 |
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