发明名称 |
Therapeutic inhibitor of vascular smooth muscle cells |
摘要 |
Methods are provided for inhibiting stenosis or restenosis following vascular trauma in a mammalian host, comprising administering to the host a therapeutically effective dosage of a cytostatic agent and/or cytoskeletal inhibitor so as to biologically stent the traumatized vessel. Also provided is a method to inhibit or reduce vascular remodeling following vascular trauma, comprising administering an effective amount of a cytoskeletal inhibitor. Further provided are pharmaceutical compositions and kits comprising the therapeutic agents of the invention.
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申请公布号 |
US6720350(B2) |
申请公布日期 |
2004.04.13 |
申请号 |
US20020330834 |
申请日期 |
2002.12.27 |
申请人 |
SCIMED LIFE SYSTEMS, INC. |
发明人 |
KUNZ LAWRENCE L.;KLEIN RICHARD A.;RENO JOHN M. |
分类号 |
A61K9/00;A61K31/00;A61K31/04;A61K31/131;A61K31/135;A61K31/138;A61K31/165;A61K31/17;A61K31/337;A61K31/352;A61K31/365;A61K31/40;A61K31/4025;A61K31/4035;A61K31/407;A61K31/519;A61K31/551;A61K31/704;A61K47/48;A61L31/08;A61L31/14;A61L31/16;A61P7/00;A61P9/00;A61P43/00;(IPC1-7):A61K31/40 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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地址 |
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