发明名称 METHOD AND APPARATUS FOR QUANTITATIVE ANALYSIS OF A TURBID, PHARMACEUTICAL SAMPLE
摘要 The present invention relates to a method and apparatuses for use in performing a quantitative analysis of a turbid pharmaceutical sample, e.g. a tablet, a capsule or a similar sample forming a pharmaceutical dose. A pharmaceutical, turbid sample (57) is irradiated with an excitation beam (53) of radiation, e.g. near infrared radiation. The intensity of emitted radiation from the sample (57) is detected as function of both the wavelength of the emitted radiation and the photon propagation time through said sample (57). Optionally, the intensity of the emitted radiation from the sample (57) is also detected in a spatially resolved manner. Preferably, the sample (57) is alnalysed with a Fourier transform spectrometer (54, 55, 56) comprising a moving a moving mirror (55) and producing an interferogram. The scanning speed of said moving mirror (55) is slower than the light source (52) modulation frequency. A phase comparator (61) compares signals from the modulation driver (50) and from the detector.
申请公布号 AU2003255807(A1) 申请公布日期 2004.04.08
申请号 AU20030255807 申请日期 2003.09.09
申请人 ASTRAZENECA AB 发明人 STEFAN ANDERSSON-ENGELS;STAFFAN FOLESTAD;JONAS JOHANSSON;SUNE SVANBERG;CHRISTOFFER ABRAHAMSSON
分类号 G01N21/35;G01N33/15;(IPC1-7):G01N21/35;G01N21/47;G01N21/64 主分类号 G01N21/35
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