| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide an asymmetric acylation catalyst usable for producing optically active alcohol compounds, amine compounds, ester compounds or amide compounds and produceable by a readily available raw material and a simple production method with good yield. <P>SOLUTION: The asymmetric catalyst uses a new optically active N-(4-pyridyl)proline ethylamide represented by formula (1) such as N-(4-pyridyl)-L-proline (S)-1'-(1-naphthyl)ethylamide which can readily be obtained by amidating proline and then reacting the product with 4-bromopyridine as the asymmetric catalyst. <P>COPYRIGHT: (C)2004,JPO |
