发明名称 |
SEQUESTERING SUBUNIT AND RELATED COMPOSITIONS AND METOHDS |
摘要 |
<p>A sequestering subunit comprising an aversive agent and a blocking agent, wherein the blocking agent substantially prevents release of the aversive agent from the sequestering subunit in the gastrointestinal tract for a time period that is greater than 24 hours; a composition comprising a sequestering subunit and a therapeutic agent in releasable form, wherein, optionally, the mechanical fragility of the sequestering subunit is the same as the mechanical fragility of the therapeutic agent in releasable form; a capsule or tablet comprising a sequestering subunit and a therapeutic agent; and a method of preventing abuse of a therapeutic agent.</p> |
申请公布号 |
WO2004026283(A1) |
申请公布日期 |
2004.04.01 |
申请号 |
WO2003US29475 |
申请日期 |
2003.09.22 |
申请人 |
ALPHARMA, INC.;BOEHM, GARTH |
发明人 |
BOEHM, GARTH |
分类号 |
A61K9/20;A61K9/24;A61K9/50;(IPC1-7):A61K9/14;A61K9/16;A61K9/28 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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