METHODE ZUM EINKAPSELN MITTELS EINES WÄSSRIGEN LÖSUNGSMITTELS UND MIKROKAPSELN

摘要

A microcapsule substantially free from non-aqueous contaminants comprising an aqueous core surrounded by a capsular wall, the capsular wall being the reaction product of a selected water soluble anionic polymer or salt thereof with a selected water soluble amine or salt thereof, the selected anionic polymer and amine having the property that, when droplets of an aqueous solution of the selected polymer are introduced into an aqueous solution of the selected amine, stable microcapsules of the amine salt of the anionic polymer are formed. The aqueous core of the microcapsule may contain any of various active ingredients, including immunogenic agents such as rotavirus. A method and apparatus for making the microcapsules, including microcapsules comprising active agents, as well as their method of use, are also disclosed.