发明名称 |
PHARMACEUTICAL COMPOSITIONS CONTAINING A SOLID DISPERSION OF A POORLY-SOLUBLE DRUG IN A MATRIX AND A SOLUBILITY-ENHANCING POLYMER. |
摘要 |
<p>A pharmaceutical composition comprises a dispersion comprising a low-solubility drug and a matrix combined with a concentration-enhancing polymer. At least a major portion of the drug is amorphous in the dispersion. The compositions improve the stability of the drug in the dispersion, and/or the concentration of drug in a use environment.</p> |
申请公布号 |
MXPA03011922(A) |
申请公布日期 |
2004.03.26 |
申请号 |
MX2003PA11922 |
申请日期 |
2002.05.13 |
申请人 |
PFIZER PRODUCTS INC. |
发明人 |
WILLIAM JOHN CURATOLO |
分类号 |
C07D215/42;A61K9/08;A61K9/14;A61K31/47;A61K47/02;A61K47/10;A61K47/12;A61K47/14;A61K47/18;A61K47/20;A61K47/24;A61K47/26;A61K47/30;A61K47/32;A61K47/34;A61K47/36;A61K47/38;A61K47/42;A61K47/44;(IPC1-7):A61K47/38 |
主分类号 |
C07D215/42 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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