发明名称 |
Polymerase chimeras |
摘要 |
The invention concerns polymerase chimeras which are composed of amino acid fragments representing domains and which combine properties of naturally occurring polymerases that are advantageous with regard to a particular application. It has surprisingly turned out that the domains from the various enzymes are active in the chimeras and exhibit cooperative behaviour. In addition the present invention concerns a process for the production of the chimeras according to the invention and the use of these chimeras for the synthesis of nucleic acids e.g. during a polymerase chain reaction. Moreover the present invention concerns a kit which contains the polymerase chimeras according to the invention.
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申请公布号 |
US2004058362(A1) |
申请公布日期 |
2004.03.25 |
申请号 |
US20030456129 |
申请日期 |
2003.06.06 |
申请人 |
ROCHE DIAGNOSTICS GMBH |
发明人 |
FREY BRUNO;VILLBRANDT BRITTA;SCHOMBURG DIETMAR;SOBEK HARALD;ANKENBAUER WALTRAUD |
分类号 |
C12N15/09;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/12;C12N9/16;C12N15/54;C12P21/02;C12Q1/68;(IPC1-7):C12Q1/68;C07H21/04;C12P19/34;C12N9/22 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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