METHODS OF DIAGNOSING AND TREATING HYPERPROLIFERATIVE DISORDERS,申请号WO2003US28742-传众专利搜索

发明名称	METHODS OF DIAGNOSING AND TREATING HYPERPROLIFERATIVE DISORDERS
摘要	The invention relates to compositions and methods for diagnosing and treating hyperproliferative disorders using ligands which specifically recognize the hypusine and/or folate binding region of mature eukaryotic translation initiation factor 5A (hypusine-containing eIF-5A). The invention further relates to methods of identifying molecules which displace immunoreagents binding to mature eIF-5A. Such agents are useful for treating hyperproliferative disorders.
申请公布号	WO2004024087(A2)	申请公布日期	2004.03.25
申请号	WO2003US28742	申请日期	2003.09.13
申请人	UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY;NIH/NIDCR;THE ROCKEFELLER UNIVERSITY;HANAUSKE-ABEL, HARTMUT, M.;PARK, MYUNG-HEE;WOLFF, EDITH, C.;SHELDON-HELLER, DEBRA;CRACCIOLO, BERNADETTE, M.;POPOWICZ, ANTHONY;CLEMENT, PAUL, M., J.	发明人	HANAUSKE-ABEL, HARTMUT, M.;PARK, MYUNG-HEE;WOLFF, EDITH, C.;SHELDON-HELLER, DEBRA;CRACCIOLO, BERNADETTE, M.;POPOWICZ, ANTHONY;CLEMENT, PAUL, M., J.
分类号	A61K;A61K48/00;C07H21/02;C07K14/47;C12Q1/68;C12Q1/70;G01N33/536;G01N33/543	主分类号	A61K
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