| 摘要 |
A process which comprises asymmetrically hydrolyzing an N-acylated DL-erythro 3-substituted serine represented by the following general formula (1): (1) (wherein R1 represents C1-10 alkanoyl, benzoyl, C1-5 alkanoyl substituted by halogeno, or benzoyl substituted by halogeno; and R2 means phenyl or cyclohexyl) with L-aminoacylase or D-aminoacylase to obtain an N-acylated D-erythro 3-substituted serine in an unreacted form or a hydrolyzed D-erythro 3-substituted serine, respectively. The D-erythro compounds are useful as an intermediate for medicines, e.g., a drug known to be useful as, e.g., an anti-HIV drug (WO 01/40227). |
