Methods for preparing purified oligonucleotides by treating a solution comprising an oligonucleotide with an aggregating agent and a precipitation enhancer under conditions sufficient to form an oligonucleotide aggregate and isolating the oligonucleotide aggregate to produce a purified oligonucleotide.</PTEXT>
申请公布号
EP1399457(A1)
申请公布日期
2004.03.24
申请号
EP20020734709
申请日期
2002.06.05
申请人
ISIS PHARMACEUTICALS, INC.
发明人
MOORE, MAX, N.;ARTHUR, JOHN, CHARLES;VANSOOY, KENT;SCOZZARI, ANTHONY, N.
