Compositions and methods for screening therapeutic agents

摘要

Methods and models for transporting agents across the blood brain barrier, the preparation of antibodies and antisense oligonucleotides, the preparation of experimental systems to study murine p97, the isolation of substances that modulate murine p97 expression and/or activity as well as the use of the murine p97 nucleic acid sequences and proteins and modulators thereof in diagnostic and therapeutic applications are described.