发明名称 |
MODIFIED TRANSFERIN-ANTIBODY FUSION PROTEINS |
摘要 |
Modified fusion proteins of transferrin and therapeutic proteins or peptides , preferably antibody variable regions, with increased serum half-life or seru m stability are disclosed. Preferred fusion proteins include those modified so that the transferrin moiety exhibits no or reduced glycosylation, binding to iron and/or binding to the transferrin receptor.
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申请公布号 |
CA2495207(A1) |
申请公布日期 |
2004.03.11 |
申请号 |
CA20032495207 |
申请日期 |
2003.08.28 |
申请人 |
BIOREXIS PHARMACEUTICAL CORPORATION |
发明人 |
SADEGHI, HOMAYOUN;PRIOR, CHRISTOPHER P.;TURNER, ANDREW J. |
分类号 |
A01K67/00;A61K38/00;A61K39/395;A61K47/48;C07D;C07H21/04;C07K14/79;C07K16/00;C07K16/24;C07K19/00;C12N15/12;C12N15/13;C12N15/62;C12N15/63;C12N15/65;C12N15/86;(IPC1-7):C12N15/62 |
主分类号 |
A01K67/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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