摘要 |
This invention discloses novel gamma secretase inhibitors of the formula: wherein: R<1 >is a substituted aryl or substituted heteroaryl group; R<2 >is an R<1 >group, alkyl, -X(CO)Y, or alkylene-X(CO)Y wherein X and Y are as defined herein; each R<3 >and each R<3A >are independently H, or alkyl; R<11 >is aryl, heteroaryl, alkyl, cycloalkyl, arylalkyl, arylcycloalkyl, heteroarylalkyl, heteroarylcycloalkyl, arylheterocycloalkyl, or alkoxyalkyl. Also disclosed is a method of treating Alzheimer's Disease using one or more compounds of the invention.
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