| 摘要 |
Reagents which regulate human membrane-type serine protease activity and reagents which bind to human membrane-type serine protease gene products can be used to regulate extracellular matrix degradation. Such regulation is particularly useful for treating cancer (e.g., suppressing metastasis of malignant cells), neurodegenerative diseases, osteoporosis, and chronic obstructive pulmonary disease.
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