发明名称 |
ANTIDIABETIC 2-SUBSTITUTED-5'-O- (1-BORANOTRIPHOSPHATE) ADENOSINE DERIVATIVES |
摘要 |
2-Substituted-5'-O-(1-boranotriphosphate)adenosine derivatives having at position 2 a radical R1 selected from the group consisting of H; halogen; O-hydrocarbyl; S-hydrocarbyl; NR3R4; and hydrocarbyl optionally substituted by halogen, CN, SCN, NO2, OR3, SR3 or NR3R4; wherein R3 and R4 are each independently H or hydrocarbyl or R3 and R4 together with the nitrogen atom to which they are attached form a saturated or unsaturated heterocyclic ring optionally containing 1-2 further heteroatoms selected from oxygen, nitrogen and sulfur, and pharmaceutically acceptable salts or diastereoisomers thereof or a mixture of diastereoisomers, are useful for treatment of type 2 diabetes. |
申请公布号 |
WO03034978(A3) |
申请公布日期 |
2004.03.11 |
申请号 |
WO2002IL00845 |
申请日期 |
2002.10.23 |
申请人 |
BAR-ILAN UNIVERSITY;UNIVERSITY OF MONTPELLIER I;FISHER, BILHA;KLEIMAN-NAHUM, VICTORIA;PETIT, PIERRE |
发明人 |
FISHER, BILHA;KLEIMAN-NAHUM, VICTORIA;PETIT, PIERRE |
分类号 |
A61K31/7076;A61P3/10;A61P43/00;C07H19/20 |
主分类号 |
A61K31/7076 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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