发明名称 |
ARIPIPRAZOLE COMPLEX FORMULATION AND METHOD |
摘要 |
<p>An aripiprazole formulation is provided which includes the antipsychotic agent aripiprazole in the form of an inclusion complex in aβ-cyclodextrin, preferably, sulfobutyl etherβ-cyclodextrin (SBECD), which in the form of an injectable produces reversible generally minimal to mild irritation at the intramuscular injection site. A method for minimizing or reducing irritation caused by aripiprazole at an intramuscular injection site and a method for treating schizophrenia employing the above formulation are also provided.</p> |
申请公布号 |
AU2003269965(A1) |
申请公布日期 |
2004.03.11 |
申请号 |
AU20030269965 |
申请日期 |
2003.08.14 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
MANOJ NERURKAR;VIJAY NARINGREKAR;MARK DOMINICK |
分类号 |
A61K31/19;A61K9/00;A61K31/496;A61K31/715;A61K31/724;A61K47/12;A61K47/48;C08B37/16 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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