| 发明名称 |
Heteroaromatic bicyclic derivatives useful as anticancer agents |
| 摘要 |
<p>The invention relates to compounds of the formula 1 <CHEM> and to pharmaceutically acceptable salts and solvates thereof, wherein A, X, R<1>, R<3> and R<4> are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.</p> |
| 申请公布号 |
EP1396489(A1) |
申请公布日期 |
2004.03.10 |
| 申请号 |
EP20030024331 |
申请日期 |
1999.12.24 |
| 申请人 |
PFIZER PRODUCTS INC. |
发明人 |
KATH, JOHN CHARLES;TOM, NORMA JACQUELINE;COX, ERIC DAVID;BHATTACHARYA, SAMIT KUMAR |
| 分类号 |
C07D401/10;A61K45/06;A61P35/00;C07D239/94;C07D403/10;C07D405/12;C07D451/02;C07D453/02;(IPC1-7):C07D239/94;A61K31/505;C07D451/08 |
主分类号 |
C07D401/10 |
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