摘要 |
A method for prevention or treating myocarditis, dilated cardiomyopathy and heart failure comprising administering to a patient in need of such treatment a NF-kappaB inhibitor in a therapeutically effective amount, wherein said NF-kappaB inhibitor is a benzoquinone derivative represented by the following formula (I):whereinR1, R2 and R3 are each independently a hydrogen atom, an alkyl group having 1 to 5 carbons or an alkoxy group having 1 to 5 carbons;R<4 >is a hydrogen atom, a hydroxymethyl group, an alkyl group, or a carboxyl group which is optionally esterified or amidated;Z isand n is an integer from 0 to 6,or its hydroquinone form, or a pharmaceutically acceptable salt thereof, is provided.
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