发明名称 Methods and products related to genotyping and DNA analysis
摘要 The invention encompasses methods and products related to genotyping. The method of genotyping of the invention is based on the use of single nucleotide polymorphisms (SNPs) to perform high throughput genome scans. The high throughput method can be performed by hybridizing SNP allele-specific oligonucleotides and a reduced complexity genome (RCG). The invention also relates to methods of preparing the SNP specific oligonucleotides and RCGs, methods of fingerprinting, determining allele frequency for a SNP, characterizing tumors, generating a genomic classification code for a genome, identifying previously unknown SNPs, and related compositions and kits.
申请公布号 US6703228(B1) 申请公布日期 2004.03.09
申请号 US19990404912 申请日期 1999.09.24
申请人 MASSACHUSETTS INSTITUTE OF TECHNOLOGY 发明人 LANDERS JOHN;JORDAN BARBARA;HOUSMAN DAVID E.;CHAREST ALAIN
分类号 C12Q1/68;G06F17/30;G06F19/00;(IPC1-7):C12Q1/68;C12P19/34;C07H21/04;G01N33/48 主分类号 C12Q1/68
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