发明名称 SCREENING METHOD FOR MORPHOGENESIS INDUCTIVE PROTEIN
摘要 PROBLEM TO BE SOLVED: To provide a screening method for a compound which brings a change to a morphogenesis inductive protein (morphogen) level produced by a tissue of an organ, when it is dosed with the compound. SOLUTION: This is a method for screening a candidate compound, capable of controlling a locally or systemically effective amount or level of the morphogen in a living matter. This method is also capable of increasing or decreasing production of the morphogen in vivo, thereby is capable of modifying pathological condition, and is capable of using for identifying a hopeful compound for a medicine for human beings. After that, the candidate compound can be used for controlling effective concentration of the morphogen in medical treatment. COPYRIGHT: (C)2004,JPO
申请公布号 JP2004069670(A) 申请公布日期 2004.03.04
申请号 JP20030014941 申请日期 2003.01.23
申请人 CURIS INC 发明人 SMART JOHN E;OPPERMANN HERMANN;OZKAYNAK ENGIN;KUBERASAMPATH THANGAVEL;RUEGER DAVID C;PANG ROY H L;COHEN CHARLES M
分类号 G01N33/50;A61K38/00;C07K14/495;C07K14/51;C07K14/52;C07K14/625;C07K16/00;C07K16/22;C12N15/09;C12Q1/02;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;G01N33/68;G01N33/74;(IPC1-7):G01N33/50 主分类号 G01N33/50
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